Download An atlas of human blastocysts by Lucinda L. Veeck, Nikica Zaninovic PDF

By Lucinda L. Veeck, Nikica Zaninovic

Should you had a in charge procedure for settling on the healthiest and such a lot conceivable conceptus from a cohort of becoming preembryos, exchanging greater than a unmarried one so that it will in achieving sturdy being pregnant charges will be moot. someday within the not-so-distant destiny, this can be a truth. Taking a step in the direction of that destiny, An Atlas of Human Blastocysts vividly illustrates the common and abnormal morphology of mammalian blastocysts. The atlas demonstrates that prolonged tradition of blastocysts is now achievable within the laboratory and issues us towards the day whilst will probably be attainable to choose from a few fit hatched blastocysts.

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Fertil Steril 1989; 51:820–7 76. Morgan K, Wiemer K, Steuerwald N, Hoffman D, Maxson W, Godke R. Use of videocinematography to assess morphological qualities of conventionally cultured and cocultured embryos. Hum Reprod 1995; 10:2371–6 77. Garside WT, Loret de Mola JR, Bucci JA, Tureck RW, Heyner S. Sequential analysis of zona thickness during in vitro culture of human zygotes: correlation with embryo quality, age, and implantation. Mol Reprod Dev 1997; 47:99–104 78. Kligman I, Benadiva C, Alikani M, Munne S.

Hum Reprod 1990; 5:109–15 42. Wiker S, Malter H, Wright G, Cohen J. Recognition of paternal pronuclei in human zygotes. J In Vitro Fertil Embryo Transf1990; 7:33–7 43. Zamboni L. In Fine Morphology of Mammalian Fertilization, 1st edn. New York: Medical Department, Harper & Row, 1971 44. Sathananthan AH, Trounson AO. The human pronuclear ovum: fine structure of monospermic and polyspsermic fertilization in vitro. Gamete Res 1985; 12:385 45. Payne D, Flaherty SP, Barry MF, Matthews CD. Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography.

The significance of enzyme isoforms and their relative changes in abundance in terms of embryo physiology/metabolism has not been fully determined, although it is evident that the isoforms of key enzymes do change during the pre- and peri-implantation period1,48,49. Different isoforms vary in their response to specific regulators of enzyme function, and could therefore help to explain the observed metabolic responses of different stages of development to their environment in culture3. Is glucose toxic to the embryo?

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