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272 Complete genome sequences are assembled from smaller pieces. 272 Sequences that are repeated complicate sequence assembly. 273 ? Why sequence your personal genome? 2 Genome Annotation 274 275 292 Across the genome as a whole, mutation is common. 293 Only germ-line mutations are transmitted to progeny. 293 ? What can your personal genome tell you about your genetic Genome annotation identifies various types of sequence. 275 risk factors? 294 Genome annotation includes searching for sequence motifs.

Griffis, Joliet Junior College Nancy A. Guild, University of Colorado, Boulder Lonnie Guralnick, Roger Williams University Valerie K. Haftel, Morehouse College Margaret Hanes, Eastern Michigan University Sally E. Harmych, University of Toledo Sherry Harrel, Eastern Kentucky University J. Scott Harrison, Georgia Southern University Pat Harrison, University of the Fraser Valley Diane Hartman, Baylor University Wayne Hatch, Utah State University Eastern David Haymer, University of Hawaii at Manoa Chris Haynes, Shelton State Community College Christiane Healey, University of Massachusetts, Amherst David Hearn, Towson University Marshal Hedin, San Diego State University Triscia Hendrickson, Morehouse College Albert A.

16 Evolution can be studied by means of experiments. 17 HOW DO WE KNOW? 6 3 laboratory? 18 Ecological Systems 19 Basic features of anatomy, physiology, and behavior shape ecological systems. 19 Ecological interactions play an important role in evolution. 20 The Human Footprint 20 ? 1 The Scientific Method 4 Observation allows us to draw tentative explanations called hypotheses. 4 A hypothesis makes predictions that can be tested by observation and experiments. 5 General explanations of natural phenomena supported by many experiments and observations are called theories.

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